ABSTRACT
OBJECTIVE@#To evaluate the effect of scaling and root planing (SRP) on serum C-reactive protein (CRP) levels in patients with moderate to severe chronic periodontitis.@*METHODS@#We searched the PubMed, Web of Science, EMBASE, Cochrane, CNKI, Wanfang, and VIP databases from the inception to July 8th, 2019. Two reviewers independently screened literature, extracted data, and evaluated the bias risk of included studies. Then, a meta-analysis was performed using RevMan 5.3 software.@*RESULTS@#A total of 13 randomized controlled clinical trials and 12 prospective clinical trials were included. Meta-analysis showed that serum CRP levels decreased at 2 and 3 months after SRP (P<0.05), and no significant difference in serum CRP levels was found at 6 months (P=0.49).@*CONCLUSIONS@#SRP can reduce serum CRP levels in systematically healthy patients with moderate to severe chronic periodontitis at 2 and 3 months after SRP.
Subject(s)
Humans , C-Reactive Protein , Chronic Periodontitis , Dental Scaling , Prospective Studies , Root PlaningABSTRACT
Objective ToexaminetheriskfactorsoftypeIIdiabetesinruralareaofHainingcityinordertoprovidebasis fordiseasecontrolandprevention.Methods Residentsagedover18infourtownswereselectedthroughmulti-stage stratified cluster random sampling method,and a questionnaire investigation,physical examination and blood biochemical indicatortestingwereconducted.Results TheadjustedprevalenceoftypeIIdiabetesinHainingcitywas5.17%overall with 5.81% in men and 4.56% in women.The results of multivariate logistic regression analysis showed that age (OR=1.78),overweight (OR=1.71),family history of diabetes (OR=16.05)were risk factors (all P<0.05).Conclusion The prevalence of type II diabetes is considerably high in rural area of Haining city. Risk factor monitoring and comprehensive intervention should strongly be advocated.